Global Opioid-Induced Constipation Treatment Market Will Boom to $650 Million by 2019

Date: 2016-02-28

The opioid-induced constipation treatment market across the six major countries of the US, Germany, France, Italy, Spain and the UK will increase from an estimated $66.7 million in 2014 to $652.4 million by 2019, representing a rapid Compound Annual Growth Rate (CAGR) of 57.8%.

Claire Gibson, Ph.D., GlobalData’s Analyst covering Cardiovascular and Metabolic Disorders, says that the introduction of novel targeted oral therapies for opioid-induced constipation, such as peripherally-acting mu-opioid receptor antagonists (PAMORAs), will be a major driver of market growth during the forecast period.

Gibson explains: “While there is currently only one approved PAMORA, AstraZeneca’s Movantik, the anticipated approval of another four PAMORAs in the US and Europe during the forecast period will mark a shift in the way that drugs for opioid-induced constipation are prescribed.

“Although laxatives are likely to remain the first-line therapy, the advent of these highly-targeted drugs will increase the number of patients receiving non-laxative prescription treatments for opioid-induced constipation.”

It also states that the majority of sales will come from the US, which will represent approximately 86% of the total market in 2019.

Gibson continues: “The US is responsible for consuming 80% of the global opioid supply, despite making up just 4.6% of the global population. Opioids are the most commonly prescribed class of medication in the US, which is mainly due to an increasing awareness of chronic pain and its effect on patient quality of life.


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