This report details the worldwide incidence and prevalence by country/region of Type 1 and Type 2 diabetes and details the current and projected market for diagnostic and therapeutic products in the management of diabetes, including anti-diabetic drugs, alternative insulin types, blood glucose monitoring (including continuous monitoring devices), insulin pumps, and other established and emerging products in diabetes management. The report provides an emphasis of detail on the status of development of novel products including noninvasive monitoring, oral/inhaled/other insulin delivery. The report details the clinical and technology developments underlying this huge and evolving worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity. Separate size, growth and competitor share data are presented for the U.S., European, Asia/Pacific and Rest of World. The report profiles active companies including detailed profile information on major competitors, brief profilThe report establishes the current worldwide market size for major technology segments as a baseline for and projecting growth in the market over a ten-year forecast. The report also assesses and projects the composition of the market as technologies gain or lose relative market performance over this period.es of companies with less sizeable current or potential positions in the market, plus additional profiles of companies with novel or advanced research activities in the market.
EXECUTIVE SUMMARY
Some Diabetes Basics
A Large and Growing Market
A Many-Sided Market
Pharmaceuticals for Diabetes Insulin
Oral Antidiabetic Drugs
The Pharmaceutical Diabetes Market
Insulin Administration Devices
Medical Devices for Diabetes
Total Diabetes Market
Regional Segmentation
Market Growth
The Diabetes Industry
Pharmaceutical Companies
Medical Device Companies
SECTION 1: ABOUT DIABETES
1.1 What is Diabetes?
1.2 Blood Sugar Regulation
1.2.1 Insulin
1.3 Main Types of Diabetes
1.3.1 Type 1 Diabetes
1.3.2 Type 2 Diabetes
1.3.3 Gestational Diabetes
1.3.4 Obesity-Related Type 2 Diabetes in Children
1.3.5 Mature-Onset Diabetes of the Young (MODY)
1.3.6 Other Diabetic States
1.4 Diagnosis
1.4.1 Glucose Tests
1.4.2 Official Criteria
1.4.3 Differential Diagnosis
1.4.3.1 Type 1 Diabetes
1.4.3.2 Type 2 Diabetes
1.5 Current Treatment
1.5.1 Type 1 Diabetes
1.5.2 Type 2 Diabetes
1.5.3 Diet
1.6 Future Treatment Approaches
1.7 Treatment Monitoring
1.7.1 Blood Sugar Control
1.7.2 The Diabetes Control and Complications Trial
1.7.3 Glycated Hemoglobin (HbA1c)
1.7.4 Fructosamine
1.8 Incidence and Prevalence of Diabetes (Type 1 & Type 2)
1.8.1 Worldwide
1.8.1.1 Type
1.8.1.2 Type
1.8.2 United States
1.8.3 Japan
1.8.4 Europe
1.9 Diabetic Complications
1.9.1 Retinopathy
1.9.2 Neuropathy
1.9.3 Nephropathy
1.10 Metabolic Syndrome
SECTION 2: PRODUCTS USED IN DIAGNOSIS AND MONITORING
2.1 Blood Glucose Monitoring Devices: Suppliers and Products
2.1.1 Lancets
2.1.2 Blood Sampling Devices
2.1.3 Blood Glucose Monitors
2.1.4 New Developments in Glucose Testing
2.2 Artificial Pancreas
2.3 Other Testing Approaches
2.3.1 Hemoglobin A1c
2.3.1.1 Hemoglobin A1c Meters
2.3.1.2 Hemoglobin A1c Kits
2.4 Software Programs for Diabetes Monitoring
2.4.1 Web Software
2.4.2 Commercial Software
SECTION 3: PRODUCTS USED IN TREATMENT
3.1 Insulin
3.1.1 History
3.1.1.1 Bovine and Porcine Insulin
3.1.1.2 Humanized Insulin
3.1.2 Companies Supplying Insulin
3.1.3 Insulin Delivery
3.1.3.1 Syringes
3.1.3.2 Insulin Syringe Manufacturers
3.1.3.3 Pens
3.1.3.4 Manufacturers of Insulin Pens
3.1.3.5 Injectors
3.1.3.6 Injector Manufacturers
3.1.4 Inhaled insulin
3.1.5 Insulin Pumps
3.1.5.1 What is an Insulin Pump?
3.1.5.2 The Infusion Set
3.1.5.3 Candidates for Pump Therapy
3.1.6 Companies Supplying Insulin Pumps
3.2 Oral Hypoglycemic Agents
3.2.1 Sulfonylureas
3.2.2 Biguanides
3.2.3 Alpha-Glucosidase Inhibitor
3.2.4 Thiazolinediones/Glitazones
3.2.5 Prandial Glucose Regulators/Meglitinides
3.2.6 Incretin Mimetics/GLP-1 Analogs
3.2.7 DPP-4 Inhibitors
3.2.8 Amylin Mimetic
3.2.9 SGLT2 Inhibitors
3.2.10 Other
SECTION 4: NOVEL APPROACHES TO DIABETES MANAGEMENT
4.1 Pancreas Transplants
4.2 Islet Cell Transplants
4.2.1 Edmonton Protocol
4.2.2 Improving Islet Cell Transplantation
4.2.3 Living-Donor Islet Cell Transplant
4.3 Stem Cell Developments
4.3.1 Embryonic Stem Cells
4.3.2 Cord Blood Stem Cells
4.3.3 Adult Stem Cells
4.4 Antibody Treatment
4.5 Vaccines
4.6 Novel Drugs
4.6.1 PPAR?/? Ligands (PPAR Co-agonists)
4.6.2 SGLT1/SGLT2 Inhibitors
4.7 Continuous Glucose Monitoring
4.7.1 Optical Glucose Sensor and Optical Biosensors
4.7.2 Sensor Based on Carbon Nanotubes
SECTION 5: THE DIABETES MARKET
5.1 Worldwide Market
5.1.1 Size
5.1.2 Growth
5.1.3 Regional Segmentation
5.2 Market Analysis by Product Category
5.2.1 Monitoring Products
5.2.1.1 Major Suppliers
5.2.2 Insulins and Insulin Delivery Devices
5.2.2.1 Major Suppliers
5.2.2.1.1 Insulin
5.2.2.1.2 Syringes and Other Insulin Administration Devices
5.2.2.1.3 Insulin Pumps
5.2.3 Anti-diabetic Drugs
5.2.3.1 Major Suppliers
5.3 Trends
5.4 Global Markets by Region
5.4.1 United States
5.4.2 Europe
5.4.3 Asia/Pacific
5.4.4 Rest of World
SECTION 6: COMPANY PROFILES
6.1 Leading Companies
6.1.1 Abbott
6.1.2 Bayer
6.1.3 Becton Dickinson
6.1.4 Bristol-Myers Squibb
6.1.5 Eli Lilly
6.1.6 GlaxoSmithKline
6.1.7 Johnson & Johnson
6.1.8 Medtronic
6.1.9 Merck & Co. / Merck Sharp & Dohme
6.1.10 Merck KGaA / Merck Serono
6.1.11 Novartis (Sandoz)
6.1.12 Novo Nordisk
6.1.13 Roche (Roche Diabetes Care)
6.1.14 Sanofi-Aventis
6.1.15 Takeda Pharmaceutical Company Limited
6.2 Other Companies
6.2.1 77 Elektronika
6.2.2 ACON Laboratories
6.2.3 Activa Brand Products, Inc.
6.2.4 AgaMatrix, Inc.
6.2.5 AiMedics Pty Ltd.
6.2.6 Alkermes Inc.
6.2.7 AmbiMedInc
6.2.8 Amylin Pharmaceuticals
6.2.9 Antares Pharma
6.2.10 Apex Biotechnology Ltd.
6.2.11 Arena Pharmaceuticals
6.2.12 ArKal Medical
6.2.13 ARKRAY USA, Inc. (formerly HypoGuard)
6.2.14 Asante Solutions, Inc.
6.2.15 B. Braun Melsungen AG
6.2.16 Biocon
6.2.17 Biodel
6.2.18 Bioject Medical Technologies Inc.
6.2.19 Biorasis Inc. (aka Bio-Orasis)
6.2.20 Biosign Technologies Inc.
6.2.21 Biovitrum
6.2.22 Boehringer Ingelheim Pharmaceuticals, Inc.
6.2.23 Calibra Medical, Inc.
6.2.24 Calisto Medical, Inc.
6.2.25 Cascade Metrix, Inc.
6.2.26 Cellnovo
6.2.27 CeQur SA
6.2.28 CPEX Pharmaceuticals
6.2.29 DARA BioSciences, Inc.
6.2.30 DexCom, Inc.
6.2.31 Diabetes Technologies, Inc.
6.2.32 Diamyd Medical AB
6.2.33 Diosynth Biotechnology
6.2.34 Echo Therapeutics
6.2.35 EnGene
6.2.36 EPS Bio Technology Corp.
6.2.37 Eumed Biotechnology Co., Ltd.
6.2.38 Exsulin Corp.
6.2.39 EyeSense
6.2.40 FivePrime Therapeutics
6.2.41 FlexSite Diagnostics
6.2.42 Freedom Meditech
6.2.43 Generex Biotechnology Corp.
6.2.44 Geron Corp.
6.2.45 GlucoPlus, Inc.
6.2.46 GluMetrics, Inc.
6.2.47 HemoCue AB
6.2.48 HMD BioMedical Inc. (aka Beijing HMD BioMedical Inc.)
6.2.49 Home Diagnostics Inc.
6.2.50 INJEX – Equidyne Systems (DBA) (Owned by HNS International)
6.2.51 InLight Solutions Inc.
6.2.52 Insulet Corporation
6.2.53 Integrity Applications Ltd.
6.2.54 InteKrin Therapeutics
6.2.55 Kumetrix Inc.
6.2.56 Laboratorios Beta
6.2.57 Lein Applied Diagnostics Ltd.
6.2.58 Ligand Pharmaceuticals Inc.
6.2.59 LighTouch Medical, Inc.
6.2.60 Living Cell Technologies, Ltd.
6.2.61 MannKind Corp.
6.2.62 Medingo Ltd.
6.2.63 Medipacs, Inc.
6.2.64 Menarini
6.2.65 Metabolex
6.2.66 NanoMega Medical
6.2.67 Nektar Therapeutics
6.2.68 NiliMEDIX Ltd.
6.2.69 Nipro Diabetes Systems Inc.
6.2.70 OK Biotech Co. Ltd.
6.2.71 Owen Mumford
6.2.72 Pfizer
6.2.73 Phenomix Corporation
6.2.74 Polymer Technology Systems Inc.
6.2.75 Prodigy Diabetes Care, LLC
6.2.76 Quotient Diagnostics Ltd.
6.2.77 Rheamed Biotechnology Co.
6.2.78 Sanwa Kagaku Kenkyusho Co. Ltd.
6.2.79 Sensors for Medicine and Science, Inc.
6.2.80 Sensys Medical
6.2.81 Sernova Corp.
6.2.82 Servier Laboratories
6.2.83 Siemens Healthcare
6.2.84 Sirna Therapeutics
6.2.85 Skyup Technology Corp.
6.2.86 SmartCells, Inc.
6.2.87 Smiths Medical
6.2.88 SOOIL Development Co., Ltd.
6.2.89 Syndexa Pharmaceuticals Corp.
6.2.90 TaiDoc Technology Corporation
6.2.91 Tandem Diabetes Care, Inc.
6.2.92 Terumo Medical Corporation
6.2.93 Theratechnologies Inc.
6.2.94 Thermalin Diabetes, Inc.
6.2.95 Tolerx Inc.
6.2.96 Tyson Bioresearch
6.2.97 Ultradian Diagnostics
6.2.98 Unilife Corp.
6.2.99 US Diagnostics Inc.
6.2.100 Valeritas, Inc.
6.2.101 Vaxine Pty Ltd.
6.2.102 VeraLight Inc.
6.2.103 Verva Pharmaceuticals
6.2.104 Visgeneer
6.2.105 VivoMedical Inc.
6.2.106 Wockhardt Ltd.
6.2.107 XOMA
6.2.108 Ypsomed AG
APPENDIX: LIST OF COMPANIES
